Transaction in Own Shares

AstraZeneca PLC
24 September 2007




REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 235,946 ordinary shares of AstraZeneca PLC at a price of 2433 pence
per share on 21 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,476,175,437.



G H R Musker
Company Secretary
24 September 2007




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