Transaction in Own Shares

AstraZeneca PLC
29 March 2006



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 28 March 2006, it purchased for cancellation
500,000 ordinary shares of AstraZeneca PLC at a price of 2902 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,578,537,545.


G H R Musker
Company Secretary
29 March 2006



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