Transaction in Own Shares

AstraZeneca PLC
20 September 2007



This announcement replaces that issued under RNS No. 0671E.
The 'shares in issue' number has been corrected.



REPURCHASE OF SHARES IN ASTRAZENECA PLC



Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 243,079 ordinary shares of AstraZeneca PLC at a price of 2354 pence
per share on 18 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,476,879,174.





G H R Musker
Company Secretary
19 September 2007


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