Transaction in Own Shares

AstraZeneca PLC
20 September 2007

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 238,836 ordinary shares of AstraZeneca PLC at a price of 2401 pence
per share on 19 September 2007. Upon the cancellation of these shares, the
number of shares in issue will be 1,446,640,338.



G H R Musker
Company Secretary
20 September 2007


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