Transaction in Own Shares

AstraZeneca PLC
07 November 2005

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 4 November 2005, it purchased for cancellation
600,000 ordinary shares of AstraZeneca PLC at a price of 2599 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,593,593,502.


G H R Musker
Company Secretary
7 November 2005


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