Transaction in Own Shares

AstraZeneca PLC
19 October 2006


REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its close period share repurchase programme,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 385,539 ordinary shares of AstraZeneca PLC at a price of 3411
pence per share on 18 October 2006. Upon the cancellation of these shares, the
number of shares in issue will be 1,545,842,427.


G H R Musker
Company Secretary
19 October 2006


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