Transaction in Own Shares

AstraZeneca PLC
25 May 2006


REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 24 May 2006, it purchased for cancellation
1,000,000 ordinary shares of AstraZeneca PLC at a price of 2802 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,569,906,365.

G H R Musker
Company Secretary
25 May 2006


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