Transaction in Own Shares

AstraZeneca PLC
29 November 2007



REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 28 November 2007, it purchased for
cancellation 625,000 ordinary shares of AstraZeneca PLC at a price of 2240 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,459,381,008.



G H R Musker
Company Secretary
29 November 2007


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