Transaction in Own Shares

AstraZeneca PLC
05 October 2006

               REPURCHASE OF SHARES IN ASTRAZENECA PLC

Further to the announcement of its close period share repurchase programme,
AstraZeneca PLC announced that under the terms of that programme it purchased
for cancellation 395,338 ordinary shares of AstraZeneca PLC at a price of 3328
pence per share on 4 October 2006. Upon the cancellation of these shares, the
number of shares in issue will be 1,549,703,344.



G H R Musker
Company Secretary
5 October 2006


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