Transaction in Own Shares

AstraZeneca PLC
11 May 2006

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 10 May 2006, it purchased for cancellation
700,000 ordinary shares of AstraZeneca PLC at a price of 2951 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,579,576,981.


G H R Musker
Company Secretary
11 May 2006



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