Transaction in Own Shares

AstraZeneca PLC
25 July 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC





Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 214,411 ordinary shares of AstraZeneca PLC at a price of 2680 pence
per share on 24 July 2007. Upon the cancellation of these shares, the number of
shares in issue will be 1,492,641,828.





G H R Musker

Company Secretary

25 July 2007


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