Transaction in Own Shares

AstraZeneca PLC
03 February 2006


                  REPURCHASE OF SHARES IN ASTRAZENECA PLC

AstraZeneca PLC announced that on 2 February 2006, it purchased for cancellation
1,000,000 ordinary shares of AstraZeneca PLC at a price of 2635 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,581,738,461.




G H R Musker
Company Secretary
3 February 2006


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