Transaction in Own Shares

AstraZeneca PLC
17 October 2007

REPURCHASE OF SHARES IN ASTRAZENECA PLC





Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 226,176 ordinary shares of AstraZeneca PLC at a price of 2541 pence
per share on 16 October 2007. Upon the cancellation of these shares, the number
of shares in issue will be 1,471,503,325.





G H R Musker

Company Secretary

17 October 2007


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