Transaction in Own Shares

AstraZeneca PLC
10 October 2007



REPURCHASE OF SHARES IN ASTRAZENECA PLC


Further to the announcement of its irrevocable, non-discretionary share
repurchase programme for the period 2 July 2007 to 31 October 2007, AstraZeneca
PLC announced that under the terms of that programme it purchased for
cancellation 224,561 ordinary shares of AstraZeneca PLC at a price of 2558 pence
per share on 9 October 2007. Upon the cancellation of these shares, the number
of shares in issue will be 1,472,577,256.



G H R Musker
Company Secretary
10 October 2007


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