Transaction in Own Shares

AstraZeneca PLC
31 August 2006



                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 30 August 2006, it purchased for cancellation
500,000 ordinary shares of AstraZeneca PLC at a price of 3393 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,558,841,114.


G H R Musker
Company Secretary
31 August 2006



                      This information is provided by RNS
            The company news service from the London Stock Exchange