Transaction in Own Shares

AstraZeneca PLC
16 August 2006




                     REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 15 August 2006, it purchased for cancellation
350,000 ordinary shares of AstraZeneca PLC at a price of 3257 pence per share.
Upon the cancellation of these shares, the number of shares in issue will be
1,560,584,195.


G H R Musker
Company Secretary
16 August 2006


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