Total Voting Rights

AstraZeneca PLC
31 March 2008



Transparency Directive
Voting Rights and Capital



The following notification is made in accordance with the UK Financial Services
Authority Disclosure and Transparency Rule 5.6.1.   On 29 February 2008 the
issued share capital of AstraZeneca PLC with voting rights is 1,457,017,580
ordinary shares of US$0.25.   No shares are held in Treasury. Therefore, the
total number of voting rights in AstraZeneca PLC is 1,457,017,580.



The above figure for the total number of voting rights may be used by
shareholders as the denominator for the calculations by which they will
determine if they are required to notify their interest in, or a change to their
interest in, AstraZeneca PLC under the FSA's Disclosure and Transparency Rules.





G H R Musker
Company Secretary
31 March 2008






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