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AstraZeneca PLC 11 October 2000 ASTRAZENECA AND NOVARTIS SHAREHOLDERS APPROVE SYNGENTA TRANSACTION AstraZeneca PLC announces that, at its Extraordinary General Meeting held in London earlier today, shareholder approval was given for the declaration and payment by the AstraZeneca Board of a dividend of Syngenta shares to holders of AstraZeneca shares on the relevant record date. The approval of this dividend will facilitate implementation of the previously announced proposed demerger of Zeneca Agrochemicals and its merger with Novartis Agribusiness to form Syngenta. At an Extraordinary General Meeting also held today in Switzerland, the Syngenta transaction was approved by the Novartis shareholders. Completion of the transaction, which remains subject to US competition law approval, is presently anticipated to take place in mid-November. For further information: Michael Olsson: Tel. +44 (0)20 7304 5087 Ed Seage: Tel +44 (0)20 7304 5101 Jorgen Winroth: Tel. +1 609 896 4148 The contents of this press announcement have been approved by Credit Suisse First Boston (Europe) Limited and Goldman Sachs International for the purposes of section 57 of the Financial Services Act 1986. Each of Credit Suisse First Boston (Europe) Limited and Goldman Sachs International which are regulated in the UK by The Securities and Futures Authority are acting for AstraZeneca PLC and Syngenta AG and no one else in connection with the transaction and will not be responsible to anyone other than AstraZeneca PLC and Syngenta AG for providing the protections afforded to the customers of Credit Suisse First Boston (Europe) Limited or Goldman Sachs International respectively or for providing advice in relation to the transaction. No offer or invitation to acquire securities in Syngenta AG is being made now nor are offers being solicited. Any such offer or invitation will only be made in documents that have previously been published or are to be published in due course and any such acquisition should be made solely on the basis of such information contained in such documents. In order to utilise the 'Safe Harbor' provisions of the United States Private Securities Litigation Reform Act of 1995, AstraZeneca PLC is providing the following cautionary statement. This press announcement contains certain forward-looking statements with respect to the proposed demerger of Zeneca Agrochemicals and its merger with Novartis Agribusiness to form Syngenta. These statements involve risk and uncertainty because they relate to events and depend on circumstances that will occur in the future. There are a number of factors that could cause completion of the transaction to be delayed or cancelled. US SHAREHOLDERS ARE URGED TO READ THE SYNGENTA REGISTRATION STATEMENT ON FORM F-4 (FILE NO. 333-12522) DATED SEPTEMBER 18, 2000 WHICH SYNGENTA HAS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION BECAUSE IT CONTAINS IMPORTANT INFORMATION.

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