Offer Document Posted

AstraZeneca PLC 03 May 2007 PRESS RELEASE NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION IN WHOLE OR IN PART, IN, INTO OR FROM AUSTRALIA, CANADA OR JAPAN OR ANY OTHER JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION FOR IMMEDIATE RELEASE 3 May 2007 Recommended Cash Tender Offer for MedImmune by AstraZeneca Pursuant to the merger agreement with MedImmune, Inc. announced on 23 April, AstraZeneca PLC announces that its wholly-owned subsidiary, AstraZeneca Biopharmaceuticals Inc., today commenced a cash tender offer to acquire all outstanding shares of MedImmune's common stock, par value $0.01 per share, at a price of $58.00 per share. The tender offer is scheduled to expire at 12:00 Midnight, New York City time, on Thursday, 31 May 2007, unless extended. Details of the tender offer are contained in the documents that are being sent to MedImmune stockholders and will be posted on astrazeneca.com. Enquiries: AstraZeneca Media Enquiries: Steve Brown / Edel McCaffrey (London) +44 (0) 20 7304 5033/5034 Staffan Ternby (Sweden) +46 (8) 553 26107 Emily Denney (Wilmington) +1 (302) 885 3451 Analyst/Investor Enquiries: Jonathan Hunt / Mina Blair / Karl Hard (London) +44 (0) 20 7304 5087/5084/5322 Staffan Ternby (Sweden) +48 (8) 553 26107 Ed Seage / Jorgen Winroth +1 (302) 886 4065 / (212) 579 0506 Merrill Lynch (Financial Adviser to AstraZeneca) +44 (0) 20 7628 1000 Richard Girling Deutsche Bank (Joint Corporate Broker to AstraZeneca) +44 (0) 20 7545 8000 Charlie Foreman Goldman Sachs (Joint Corporate Broker to AstraZeneca) +44 (0) 20 7774 1000 Phil Raper This information is provided by RNS The company news service from the London Stock Exchange

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