Notice of AGM

AstraZeneca PLC
20 March 2006

                    NOTICE OF ANNUAL GENERAL MEETING 2006

                         AND PROPOSED BOARD CHANGES


AstraZeneca PLC announced today the publication of its Notice of Annual General
Meeting for 2006 with a covering letter from the Chairman of the Board, and a
Shareholders' Circular and Proxy Form.

A copy of the Notice of AGM and Shareholders' Circular is available on the
Company's website www.astrazeneca.com and the documents are being despatched to
shareholders from today.  The date of the AGM is 27 April 2006.

With effect from the end of the AGM, Dame Bridget Ogilvie will retire from the
Board after nine years' service as a Non-Executive Director.

Professor Dame Nancy Rothwell FRS will be proposed by the Board for election as
a new Non-Executive Director at the AGM.  Professor Rothwell is currently
Vice-President for Research at the University of Manchester.  Further
biographical details for Professor Rothwell can be found in the Notice of AGM
and Shareholders' Circular.


G H R Musker
Company Secretary
20 March 2006


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