Holding(s) in Company

AstraZeneca PLC
01 October 2004


COMPANIES ACT 1985 SECTION 198

DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES


ON 1 OCTOBER 2004 WE WERE INFORMED THAT, AS OF 29 SEPTEMBER 2004, BARCLAYS PLC
HAD A NOTIFIABLE INTEREST IN THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC OF
50,634,731 SHARES WHICH REPRESENTS 3.05 PER CENT OF THE ISSUED ORDINARY CAPITAL
OF THE COMPANY.


G H R MUSKER

COMPANY SECRETARY

1 OCTOBER 2004

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