Director Shareholding

AstraZeneca PLC
5 February 2002

DEALING BY DIRECTORS

COMPANIES ACT 1985 SECTION 324/329

WE HEREBY INFORM YOU THAT ON 4 FEBRUARY 2002 THE FOLLOWING DIRECTORS OF THE
COMPANY ACQUIRED AN INTEREST IN ASTRAZENECA PLC ORDINARY SHARES OF USD0.25 EACH.
THE INTERESTS ARISE AS A RESULT OF AN AUTOMATIC RELEASE OF SHARES OUT OF
RETENTION UNDER THE ASTRA GLOBAL PROFIT SHARING SCHEME. UNDER THE RULES OF THE
SCHEME, SHARES ARE PLACED IN TRUST AND ARE NOT BENEFICIALLY OWNED BY THE
PARTICIPANT WHILE THEY REMAIN HELD IN THE TRUST.  THE PARTICIPANT CAN MAKE AN
ANNUAL ELECTION TO WITHDRAW THE SHARES OUT OF TRUST AT WHICH TIME THE
PARTICIPANT BECOMES THE BENEFICIAL OWNER OF THE SHARES.  THE RELEASE DATE IS
USUALLY IN THE LAST WEEK OF JANUARY OR THE FIRST WEEK OF FEBRUARY EVERY YEAR,
THE ELECTION HAVING BEEN MADE IN AUGUST OF THE PREVIOUS YEAR.

NAME OF DIRECTOR     NUMBER OF SHARES    TOTAL INTEREST     PERCENTAGE OF ISSUED 
                                                                SHARES

A B T STAVLING            94                  9,023           0.001

C E WILHELMSSON          188                 27,650           0.002

THE SHARES ARE REGISTERED IN THE DIRECTORS' VPC ACCOUNTS IN SWEDEN. THE PRICE OF
ORDINARY SHARES OF ASTRAZENECA PLC AT CLOSE OF BUSINESS ON 4 FEBRUARY 2002 WAS
3345P.

G H R MUSKER
COMPANY SECRETARY

5 FEBRUARY 2002


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