3rd Quarter Results -Part 2/2

AstraZeneca PLC 23 October 2003 Consolidated Profit & Loss Account For the nine months ended 30 September 2003 2002 $m $m Sales 13,974 12,940 Cost of sales (3,412) (3,267) Distribution costs (116) (102) Research and development (2,409) (2,177) Selling, general and administrative expenses (4,907) (4,337) Other operating income 132 225 Operating profit 3,262 3,282 Net interest and dividend income 71 24 Profit on ordinary activities before taxation 3,333 3,306 Taxation (917) (886) Profit on ordinary activities after taxation 2,416 2,420 Attributable to minorities (15) (12) Net profit for the period 2,401 2,408 Dividends to shareholders (436) (398) Profit retained for the period 1,965 2,010 Earnings per Ordinary Share $1.40 $1.39 Diluted earnings per Ordinary Share $1.40 $1.39 Weighted average number of Ordinary Shares in issue (millions) 1,713 1,736 Diluted average number of Ordinary Shares in issue (millions) 1,714 1,739 Consolidated Profit & Loss Account For the quarter ended 30 September 2003 2002 $m $m Sales 4,803 4,282 Cost of sales (1,175) (1,113) Distribution costs (41) (37) Research and development (812) (757) Selling, general and administrative expenses (1,744) (1,468) Other operating income 70 14 Operating profit 1,101 921 Net interest and dividend income 18 2 Profit on ordinary activities before taxation 1,119 923 Taxation (308) (242) Profit on ordinary activities after taxation 811 681 Attributable to minorities (8) (6) Net profit for the period 803 675 Dividends to shareholders - - Profit retained for the period 803 675 Earnings per Ordinary Share $0.47 $0.39 Diluted earnings per Ordinary Share $0.47 $0.39 Weighted average number of Ordinary Shares in issue (millions) 1,710 1,728 Diluted average number of Ordinary Shares in issue (millions) 1,711 1,730 Consolidated Balance Sheet 2003 2002 As at 30 September $m $m Fixed assets 10,058 9,023 Current assets 12,996 11,557 Total assets 23,054 20,580 Creditors due within one year (7,095) (6,916) Net current assets 5,901 4,641 Total assets less current liabilities 15,959 13,664 Creditors due after more than one year (348) (491) Provisions for liabilities and charges (2,046) (1,596) Net assets 13,565 11,577 Capital and reserves Shareholders' funds and minority interests 13,565 11,577 Consolidated Cash Flow Statement 2003 2002 For the nine months ended 30 September $m $m Cash flow from operating activities Operating profit 3,262 3,282 Depreciation and amortisation 900 700 (Increase)/decrease in working capital and other non-cash movements (630) 153 Net cash inflow from operating activities before exceptional items 3,532 4,135 Outflow related to exceptional items (387) (74) Net cash inflow from operating activities 3,145 4,061 Returns on investments and servicing of finance 49 42 Tax paid (1,007) (678) Capital expenditure and financial investment (1,002) (1,034) Acquisitions and disposals 80 - Equity dividends paid to shareholders (770) (820) Net cash inflow before management of liquid resources and financing 495 1,571 Net purchase of shares (501) (871) Exchange and other movements 65 56 Increase in net cash funds in the period 59 756 Net cash funds at beginning of period 3,844 2,867 Net cash funds at end of period 3,903 3,623 Notes to the Interim Financial Statements 1 BASIS OF PREPARATION AND ACCOUNTING POLICIES The unaudited financial statements for the nine months ended 30 September 2003 have been prepared in accordance with UK generally accepted accounting principles. The accounting policies applied are those set out in AstraZeneca PLC's 2002 Annual Report and Form 20-F. These interim financial statements do not constitute statutory accounts of the group within the meaning of Section 240 of the Companies Act 1985. Statutory accounts for the year ended 31 December 2002 have been filed with the Registrar of Companies. The auditor's report on those accounts was unqualified and did not contain any statement under Section 237 of the Companies Act 1985. As part of AstraZeneca's objective to align with best accounting practice, cash discounts arising from prompt payments of invoices were reclassified from cost of sales to sales for the year ended 31 December 2002. Comparatives were reclassified and additional detail at product and territorial level are available on the AstraZeneca website. Both sales and cost of sales were reduced by $213m in the first nine months of 2002. Neither profits nor assets were affected. 2 JOINT VENTURES AND ASSOCIATES The group's share of joint ventures' sales for the nine months to 30 September 2003 amounted to $189m and $184m for the comparative period. Share of joint ventures' operating profits for the nine months to 30 September 2003 and for the comparative period, were $nil. 3 NET CASH FUNDS The table below provides an analysis of net cash funds and a reconciliation of net cash flow to the movement in net cash funds. At 1 Jan Cash Other Exchange At 30 Sept 2003 flow non-cash movements 2003 $m $m $m $m $m Loans due after 1 year (328) 18 - 6 (304) Current instalments of loans (314) 319 - (5) - Total loans (642) 337 - 1 (304) Short-term investments 3,962 (490) - 38 3,510 Cash 726 28 - 28 782 Overdrafts (202) 119 - (2) (85) 4,486 (343) - 64 4,207 Net cash funds 3,844 (6) - 65 3,903 Issue of AstraZeneca PLC Ordinary Shares (31) Repurchase of AstraZeneca PLC Ordinary Shares 532 Net cash inflow before management of liquid resources and financing 495 4 NINE MONTHS TERRITORIAL SALES ANALYSIS % Growth Nine Months Nine Months 2003 2002 Constant $m $m Actual Currency USA 6,703 6,787 (1) (1) Canada 519 423 23 15 North America 7,222 7,210 - (1) France 1,058 820 29 9 UK 394 476 (17) (25) Germany 623 503 24 5 Italy 680 551 23 4 Sweden 229 210 9 (8) Europe others 1,879 1,607 17 1 Total Europe 4,863 4,167 17 - Japan 833 663 26 18 Rest of World 1,056 900 17 18 Total 13,974 12,940 8 2 5 THIRD QUARTER TERRITORIAL SALES ANALYSIS % Growth 3rd 3rd Quarter Quarter 2003 2002 Constant $m $m Actual Currency USA 2,271 2,190 4 4 Canada 189 150 26 12 North America 2,460 2,340 5 4 France 370 287 29 8 UK 120 151 (21) (29) Germany 233 174 34 12 Italy 230 172 34 12 Sweden 77 72 7 (10) Europe others 632 523 21 5 Total Europe 1,662 1,379 21 3 Japan 297 251 18 14 Rest of World 384 312 23 17 Total 4,803 4,282 12 5 6 NINE MONTHS PRODUCT SALES ANALYSIS World US Nine Nine Constant Nine Months Months Actual Currency Months Actual 2003 2002 Growth Growth 2003 Growth $m $m % % $m % Gastrointestinal: Losec 2,037 3,508 (42) (46) 785 (64) Nexium 2,466 1,292 91 86 1,892 88 Others 53 45 18 9 18 38 Total Gastrointestinal 4,556 4,845 (6) (10) 2,695 (15) Cardiovascular: Zestril 342 733 (53) (58) 65 (85) Seloken 1,034 638 62 58 765 76 Atacand 543 409 33 23 197 30 Plendil 383 350 9 4 156 7 Tenormin 246 275 (11) (17) 14 (67) Crestor 88 - n/m n/m 56 n/m Others 284 270 5 (7) 13 (7) Total Cardiovascular 2,920 2,675 9 2 1,266 5 Respiratory: Pulmicort 674 575 17 10 348 44 Rhinocort 272 223 22 19 202 29 Symbicort 377 194 94 69 - - Accolate 76 92 (17) (19) 49 (22) Oxis 91 91 - (12) - - Others 110 106 4 (7) - - Total Respiratory 1,600 1,281 25 16 599 30 Oncology: Zoladex 630 588 7 (1) 128 (18) Casodex 647 460 41 30 187 40 Nolvadex 138 342 (60) (62) 40 (83) Arimidex 372 239 56 46 153 50 Iressa 136 26 n/m n/m 54 n/m Faslodex 56 19 195 195 55 189 Others 14 14 - (7) - - Total Oncology 1,993 1,688 18 10 617 (5) CNS: Seroquel 1,059 788 34 31 796 25 Zomig 245 234 5 (2) 110 (12) Others 20 23 (13) (26) - n/m Total CNS 1,324 1,045 27 23 906 18 Pain, Infection and Other Pharma: Diprivan 339 326 4 (1) 170 8 Merrem 242 216 12 8 40 (22) Local anaesthetics 344 311 11 4 83 9 Other Pharma Products 263 190 38 29 114 100 Total Pain, Infection and Other Pharma 1,188 1,043 14 8 407 19 Salick Health Care 200 170 18 18 200 18 Astra Tech 144 108 33 13 11 38 Marlow Foods 49 85 (42) (47) 2 - Total 13,974 12,940 8 2 6,703 (1) n/m not meaningful Other Pharma Products include contract manufacturing for Prilosec OTC 7 THIRD QUARTER PRODUCT SALES ANALYSIS World US 3rd 3rd Constant 3rd Quarter Quarter Actual Currency Quarter Actual 2003 2002 Growth Growth 2003 Growth $m $m % % $m % Gastrointestinal: Losec 631 1,200 (47) (52) 206 (74) Nexium 1,000 481 108 102 786 114 Others 18 15 20 13 7 75 Total Gastrointestinal 1,649 1,696 (3) (8) 999 (13) Cardiovascular: Zestril 116 187 (38) (44) 22 (73) Seloken 286 201 42 37 189 39 Atacand 185 131 41 29 60 62 Plendil 144 147 (2) (7) 67 (9) Tenormin 81 85 (5) (12) 1 (80) Crestor 76 - n/m n/m 56 - Others 96 89 8 (5) 4 33 Total Cardiovascular 984 840 17 9 399 18 Respiratory: Pulmicort 184 149 23 14 87 71 Rhinocort 86 79 9 6 66 12 Symbicort 128 72 78 54 - - Accolate 20 27 (26) (30) 11 (39) Oxis 31 30 3 (10) - - Others 36 34 6 (6) - - Total Respiratory 485 391 24 14 164 28 Oncology: Zoladex 224 206 9 - 44 (21) Casodex 230 189 22 12 55 (23) Nolvadex 38 85 (55) (59) 4 (92) Arimidex 136 95 43 32 52 27 Iressa 70 26 169 165 36 n/m Faslodex 19 11 73 73 18 64 Others 5 3 67 67 - - Total Oncology 722 615 17 9 209 (9) CNS: Seroquel 345 196 76 71 251 79 Zomig 83 68 22 12 32 10 Others 5 8 (38) (51) (2) n/m Total CNS 433 272 59 52 281 64 Pain, Infection and Other Pharma: Diprivan 105 104 1 (5) 47 (4) Merrem 88 75 17 9 15 (21) Local anaesthetics 121 155 (22) (28) 32 (26) Other Pharma Products 100 10 n/m n/m 55 n/m Total Pain, Infection and Other Pharma 414 344 20 12 149 32 Salick Health Care 66 57 16 16 66 16 Astra Tech 50 37 35 16 4 33 Marlow Foods - 30 n/m n/m - n/m Total 4,803 4,282 12 5 2,271 4 n/m not meaningful Other Pharma Products include contract manufacturing for Prilosec OTC Shareholder Information ANNOUNCEMENTS AND MEETINGS Announcement of fourth quarter and full year 2003 results 29 January 2004 Announcement of first quarter 2004 results 29 April 2004 Annual General Meeting 2004 29 April 2004 Announcement of second quarter and half year 2004 results 22 July 2004 Announcement of third quarter 2004 results 21 October 2004 DIVIDENDS The record date for the first interim dividend paid on 6 October 2003 (in the UK, Sweden and the US) was 22 August 2003. Ordinary Shares traded ex-dividend on the London and Stockholm Stock Exchanges from 20 August 2003. ADRs traded ex-dividend on the New York Stock Exchange from the same date. The record date for the second interim dividend for 2003 payable on 6 April 2004 (in the UK, Sweden and the US) will be 20 February 2004. Ordinary Shares will trade ex-dividend on the London and Stockholm Stock Exchanges from 18 February 2004. ADRs will trade ex-dividend on the New York Stock Exchange from the same date. Future dividends will normally be paid as follows: First interim Announced in July and paid in October Second interim Announced in January and paid in April TRADEMARKS The following brand names used in this interim report are trade marks of the AstraZeneca group of companies: Accolate Arimidex Astra Tech Atacand Casodex Crestor Diprivan Exanta Faslodex Iressa Losec Marcaine Merrem Nexium Nolvadex Oxis Plendil Prilosec Pulmicort Pulmicort Respules Pulmicort Turbuhaler Rhinocort Rhinocort Aqua Seloken Seroquel Symbicort Tenormin Toprol-XL Xylocaine Zestril Zoladex Zomig ADDRESSES FOR CORRESPONDENCE Registrar and Depositary Registered Office Swedish Securities Register Centre Transfer Office for ADRs VPC AB The AstraZeneca Registrar JPMorgan Chase Bank 15 Stanhope Gate PO Box 7822 Lloyds TSB Registrars PO Box 43013 London S-103 97 Stockholm The Causeway Providence W1K 1LN Sweden Worthing RI 02940-3013 UK West Sussex US BN99 6DA Tel: +44 (0)121 433 8000 Tel: +1 (781) 575 4328 Tel: +44 (0)20 7304 5000 Tel: +46 (0)8 402 9000 CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS In order to utilise the 'Safe Harbor' provisions of the United States Private Securities Litigation Reform Act of 1995, AstraZeneca is providing the following cautionary statement. This Interim Report contains forward-looking statements with respect to the financial condition, results of operations and businesses of AstraZeneca. By their nature, forward-looking statements and forecasts involve risk and uncertainty because they relate to events and depend on circumstances that will occur in the future. There are a number of factors that could cause actual results and developments to differ materially from that expressed or implied by these forward-looking statements. These factors include, among other things, the loss or expiration of patents, marketing exclusivity or trade marks; exchange rate fluctuations; the risk that R&D will not yield new products that achieve commercial success; the impact of competition; price controls and price reductions; taxation risks; the risk of substantial product liability claims; the impact of any failure by third parties to supply materials or services; the risk of delay to new product launches; the difficulties of obtaining and maintaining governmental approvals for products; and the risk of environmental liabilities. This information is provided by RNS The company news service from the London Stock Exchange

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