Holding in Company

Microgen PLC
5 July 2001


                  DEALINGS BY SUBSTANTIAL SHAREHOLDERS


1)   NAME OF COMPANY

      MICROGEN PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     EDINBURGH FUND MANAGERS GROUP PLC

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

      SHAREHOLDER

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     RBSTB NOMINEES LTD - 4,349,704
     CITY OF EDINBURGH COUNCIL - 275,314
     MINEWORKERS PENSION SCHEME (CHASE GIS)
     NOMINEES LTD - 815,300
     BRITISH COAL STAFF SUPERANNUATION SCHEME
     (CHASE GIS) NOMINEES LTD - 815,300
     VIDACOS NOMINEES LTD - 312,076
     NORTH CASTLE STREET (NOMINEES) LTD - 179,000

5)   Number of shares/amount of stock acquired.

     629,450

6)   (1.23%) of issued Class

7)   Number of shares/amount of stock disposed

      -

8)   ( N/A %) of issued Class

9)   Class of security

      5P ORDINARY SHARES

10)  Date of transaction

      5 JULY 2001

11)  Date company informed

      5 JULY 2001

12)  Total holding following this notification

      6,746,694
               
              
13)  Total percentage holding of issued class following this notification

      13.17%

14)  Any additional information

      

15)  Name of contact and telephone number for queries

      G.E. LIDDLE
      01753 847155

16)  Name and signature of authorised company official responsible for 
     making this notification   G.E. LIDDLE
                                COMPANY SECRETARY

     Date of Notification ...5 JULY 2001....