Directors' Dealings

MICROGEN PLC


                            DEALINGS BY DIRECTORS

1)   NAME OF COMPANY

MICROGEN PLC

2)   NAME OF DIRECTOR

RALPH THOMAS LUDWIG KANTER

3)   Please state whether notification indicates that it is in
     respect of holding of the Director named in 2 above
     or holding of that person's spouse or children under
     the age of 18 or in respect of a non-beneficial interest

DIRECTOR


4)   Name of the registered holder(s) and, if more than
     one holder, the number of shares held by each of 
     them. (If notified)

AS ABOVE

5)   Please state whether notification relates to a
     person(s) connected with the Director named in 2
     above and identify the connected person(s)

N/A

6)   Please state the nature of the transaction. For
     PEP transactions please indicate whether
     general/single co PEP and if discretionary/non
     discretionary

PURCHASED AS BENEFICIAL OWNER

7)   Number of shares/amount of
     stock acquired

6,300

8)   (0.012%)
    of issued Class

9)   Number of shares/amount
     of stock disposed

N/A

10)  ( N/A %)
    of issued Class

11)  Class of security

ORDINARY SHARES OF 5P EACH

12)  Price per share

154P

13)  Date of transaction

16/9/99

14)  Date company informed

17/9/99

15)  Total holding following this notification

32,300

16)  Total percentage holding of issued class following 
     this notification      

0.064%

      IF A DIRECTOR HAS BEEN GRANTED OPTIONS BY THE COMPANY PLEASE COMPLETE 
                              THE FOLLOWING BOXES

17)  Date of grant

N/A

18)  Period during which or date on which exercisable

N/A

19)  Total amount paid (if any) for grant of the option

N/A

20)  Description of shares or debentures involved:
     class, number.

N/A

21)  Exercise price (if fixed at time of grant) or indication
     that price is to be fixed at time of exercise

N/A

22)  Total number of shares or debentures over which
     options held following this notification

N/A

23)  Any additional information

N/A

24)  Name of contact and telephone number for queries


KIM ARCHER 01753 847 155


25)  Name and signature of authorised company official
     responsible for making this notification

     Date of Notification......17 SEPTEMBER 1999.........




                            DEALINGS BY DIRECTORS

1)   NAME OF COMPANY

MICROGEN PLC

2)   NAME OF DIRECTOR

RALPH THOMAS LUDWIG KANTER

3)   Please state whether notification indicates that it is in
     respect of holding of the Director named in 2 above
     or holding of that person's spouse or children under
     the age of 18 or in respect of a non-beneficial interest

SPOUSE         


4)   Name of the registered holder(s) and, if more than
     one holder, the number of shares held by each of 
     them. (If notified)

PATRICIA BARBARA KANTER

5)   Please state whether notification relates to a
     person(s) connected with the Director named in 2
     above and identify the connected person(s)

N/A

6)   Please state the nature of the transaction. For
     PEP transactions please indicate whether
     general/single co PEP and if discretionary/non
     discretionary

                                 

7)   Number of shares/amount of
     stock acquired

6,400

8)   (0.013%)
    of issued Class

9)   Number of shares/amount
     of stock disposed

N/A

10)  ( N/A %)
    of issued Class

11)  Class of security

ORDINARY SHARES OF 5P EACH

12)  Price per share

154P

13)  Date of transaction

16/9/99

14)  Date company informed

17/9/99

15)  Total holding following this notification

38,700

16)  Total percentage holding of issued class following 
     this notification      

0.076%

      IF A DIRECTOR HAS BEEN GRANTED OPTIONS BY THE COMPANY PLEASE COMPLETE 
                              THE FOLLOWING BOXES

17)  Date of grant

N/A

18)  Period during which or date on which exercisable

N/A

19)  Total amount paid (if any) for grant of the option

N/A

20)  Description of shares or debentures involved:
     class, number.

N/A

21)  Exercise price (if fixed at time of grant) or indication
     that price is to be fixed at time of exercise

N/A

22)  Total number of shares or debentures over which
     options held following this notification

N/A

23)  Any additional information

N/A

24)  Name of contact and telephone number for queries


KIM ARCHER 01753 847 155


25)  Name and signature of authorised company official
     responsible for making this notification

     Date of Notification.....17 SEPTEMBER 1999.....