Quarterly Trading Statement to 31 January 2024

Ananda Developments PLC
26 February 2024
 

26 February 2024

 

ANANDA DEVELOPMENTS PLC

("Ananda" or the "Company")

 

Management accounts for the quarter ended 31 January 2024

 

Ananda Developments Plc (AQUIS: ANA), the company whose ambition is to be a leading provider of cannabinoid-based medicines for the treatment of chronic, complex inflammatory pain conditions, announces its unaudited management statements for the quarter ended 31 January 2024.

 

This announcement contains inside information for the purposes of the UK Market Abuse Regulation and the Directors of the Company are responsible for the release of this announcement.

 

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ANANDA DEVELOPMENTS PLC

Chief Executive Officer

Melissa Sturgess


Executive Director

Jeremy Sturgess-Smith

 

+44 (0)7463 686 497 ir@anandadevelopments.com

SP ANGEL CORPORATE FINANCE LLP

Corporate Finance

Richard Morrison

Harry Davies-Ball

+44 (0)20 3470 0470

Corporate Broking

Abigail Wayne

Rob Rees

 


Yellow Jersey PR

Charles Goodwin

Soraya Jackson

+44 (0)20 3004 9512

 

 

Directors Statement

 

Introduction

 

Ananda Developments Plc ("the Company" or "Ananda") is a company quoted on the Aquis Stock Exchange ("AQSE") Growth Market.  The Company was incorporated on 19 January 2018 and its shares were admitted to trading on 4 July 2019.

 

Below is a summary of activities during the period in question and certain post-period events.

 

Activities during the period

 

Ananda Corporate

 

Ananda will be attending and speaking at the Master Investor Show in London at The Business Design Centre 52 Upper Street London N1 0QH on the 9th of March. The Company will be represented at the event by its CEO, Melissa Sturgess, and its Finance Director, Jeremy Sturgess-Smith.

 

To attend the show, please follow the following link: https://masterinvestorshow-2024.reg.buzz/?exhibitor-inviter=18f1c1fa-b9ee-11ee-9af7-000000000000

 

Ananda has recently opened its InvestorHub (the "Hub") for all shareholders, stakeholders and interested parties to sign up to. This was launched on 14 December 2023 with the intent to increase the Company's ability to engage directly with individual stakeholders. To join the Hub, follow the link here: https://investors.anandadevelopments.com/s/a66906

 

Also during, and just after, the period the Company announced the appointment of Professor Cherry Wainright and Dr Katie Sloper, PhD as Scientific Advisers (30 January 2024) to the Company, and Vitalii Ratushni as Data and Analytics Adviser (6 February 2024).

 

·    Professor Cherry Wainwright is a pharmacological research expert with over 42 years of experience and is the President Elect of the British Pharmacological Society ('BPS'). The mission of the BPS is to promote and advance the whole spectrum of pharmacology - the scientific study of the effects of drugs and chemicals on living organisms.  The BPS leads the way in the research and application of pharmacology around the world and has over 4,000 members from more than 60 countries worldwide.

Cherry will advise the Company on its drug development activities, areas of potential unmet need that could benefit from Ananda's medicines, and clinical trial activities including protocol development.

 

·    Dr. Katie Sloper, PhD is a medical research expert with a particular focus on the therapeutic profile of cannabis-based medicines and innovative approaches to cancer treatment. Katie's work with Ananda will focus on developing the Company's scientific understanding of cannabidiol and its mechanisms of action, with a particular focus on chronic pain and inflammation. Katie will help the Company to continually refine its scientific approach and identify potential new areas for clinical investigation.

 

·    Vitalii Ratushni is a data, analytics, and quantitative modelling expert. His appointment gives Ananda the analytical capability to better target its research activities by identifying potential current and new disease areas where cannabinoids may be efficacious. His expertise in big data will enable Ananda to assess patient populations in areas of unmet need and support new cannabinoid drug development. Vitalii's focus will be on creating a database of over 10,000 diseases which have symptoms for which cannabinoids may have potential for activity. The database will then be refined to conditions which have evidence that cannabidiol has treatment potential. Refinement and interrogation will provide Ananda with information sets to identify clinical trial research opportunities.

 

MRX Medical (MRX)

 

Clinical Trials

 

During the period, MRX continued to progress its two already announced clinical trials and to put the foundations in place for future clinical trials in other conditions. As a reminder, Ananda announced during 2023 that MRX will be supplying its patent-pending MRX1 cannabidiol oil to two Phase II trials. Those trials are investigating:

 

·    The pain relieving effects of MRX1 on sufferers of endometriosis. The RCT, funded by a £300,000 non-dilutive grant from the Chief Scientist Office in Scotland, is being led by Dr Lucy Whitaker, a Senior Clinical Research Fellow at the Centre for Reproductive Health, University of Edinburgh. The trial will be a pilot trial, with the end goal being to assess the feasibility of running a further nation-wide trial on the use of CBD versus placebo in the treatment of endometriosis-associated pain. The study will be located at NHS Lothian and NHS Grampian with a 100‑patient recruitment plan.

Endometriosis is a condition where tissue similar to the lining of the uterus grows outside the uterus. It can cause severe pain in the pelvis and affect fertility. Globally, 10% of women suffer from endometriosis* and currently the only treatments are surgery, hormonal treatment or pain killers. The global market of 190 million sufferers was valued at $1.05bn in 2020 and is expected to achieve CAGR of 9.6% from 2020-2030**. 

 

·    The pain relieving effects of MRX1 on sufferers of Chemotherapy Induced Peripheral Neuropathy ("CIPN"). This trial, funded by a £1.25m non-dilutive grant, is being led by Professor Marie Fallon who is a leading researcher at the University of Edinburgh (the "UoE") and the St Columba's Hospice Chair of Palliative Medicine as well as Honorary Consultant in Palliative Care with 256 publications and over 10,000 citations. The trial will be a double-blind crossover trial, located at Western General Hospital with a 92 patient recruitment plan. CIPN is a common and debilitating side effect of chemotherapy with approximately 160,000 new cases per year in the UK, with a prevalence of 60% 3 months after chemotherapy treatment.  

Signing of Drug Supply Agreement

 

On 14 November 2023, the Company announced that MRX has signed a Drug Supply Agreement ("DSA") with the UoE and the Lothian Health Board ("LHB"). This agreement provides the legal framework for the provision of MRX1 to UoE for the CIPN trial and confirms that MRX has been granted a licence over all arising (generated from the trial) Intellectual Property ("IP") for internal research and development purposes, as well as an option to licence the arising IP for all commercial purposes. MRX will maintain full ownership of all IP as relates to the Investigative Medicinal Product (MRX1) and its matching Placebo. There are no preventative treatments for CIPN and symptom management is commonly ineffective. The CIPN global market was valued at US$1bn in 2021 and is estimated to reach US$1.5bn in 2030 and, given most treatments are ineffective, the Directors believe that this figure may not accurately reflect the true market size.

 

Patents

 

On 8 November 2023, the Company announced that MRX has filed a fifth patent application with the UK Government's Intellectual Property Office. The application covers a new cannabinoid formulation known as MRX2T. This formulation is based on MRX's patent pending MRX2 cannabidiol formulation, with the addition of tetrahydrocannabinol ("THC"). This formulation has been developed for use in Randomised Controlled Trials ("RCTs"). This application is in addition to four previous applications which cover the proprietary formulation methodology and three different cannabinoid formulations known as MRX1, MRX2 and MRX3.

 

Throughout the remainder of the period the team at MRX pressed on diligently with MRX's research partners, and we look forward to bringing all our shareholders more information on this and any other developments at MRX as soon as possible.

 

DJT

 

At the beginning of the period, on 1 November 2023, the Company announced that Ananda and DJT had signed a Memorandum of Understanding ("MOU") with Nottingham Trent University ("NTU") to pursue third-party grant funding to progress DJT's medical cannabis breeding programme and its low-carbon medical cannabis cultivation and manufacturing. The shared vision, beyond the MOU, is to create a formal strategic partnership and the establishment of a Cannabinoid Centre of Excellence at NTU.

 

Throughout the period the Company's Head of Operations continued discussions with NTU's Grant Capture department to begin assessing which grants were most appropriate for DJT to apply for. Our Finance Director has also worked to reduce DJT's monthly cash burn as far as possible to preserve Company cash.

 

Whilst we continue to believe that DJT shows incredible promise as a business unit, until the market demand increases and the regulatory framework becomes less opaque the Directors believe that MRX is the Company's core value driver and the Company will be applying most of its efforts and resources in this area in the near term.

 

Melissa Sturgess

Chief Executive Officer

 

* https://www.who.int/news-room/fact-sheets/detail/endometriosis

**https://www.globaldata.com/store/report/endometriosis-market-analysis/#:~:text=What%20is%20the%20endometriosis%20market,9%25%20during%202020%2D2030.

Unaudited Statement of Comprehensive Income for the quarter ended 31 January 2024

 



Note

31 January 2024

 



 

£





Administrative expenses



(195,653)





Interest payable



(48,669)





Loss from operations



(244,322)





Taxation



-





Total loss for the period


 

(244,322)

 

 

Earnings per share


 

 

Basic and diluted earnings per share (pence)


2

(0.008p)

 

 

There was no other comprehensive income in the period.

 

The notes which follow form part of these management accounts.

 

Statement of Financial Position As at quarter ended 31 January 2024

 



Note

31 January 2024

 



 

£

Non-Current assets




Investments in subsidiaries



9,876,229



 

9,876,229

Current assets




Trade and other receivables



48,850

Cash and cash equivalents


1

-



 

48,850

 




Current liabilities




Trade and other payables



2,129,629



 

2,129,629

Non-Current liabilities




Convertible loan notes



636,507





Total assets less liabilities


 

7,158,942





Capital and reserves




Share capital



5,756,056

Share premium



5,328,996

Share option reserve



70,216

Retained earnings



(3,996,326)





Total equity and liabilities


 

7,158,942

 


 

 

The Company does not have a bank account.  Ananda's cash is held by its subsidiary companies DJT Plants Ltd and MRX Global Limited.  As at 31 January 2024, the subsidiaries jointly held cash of £84,428.

 

The management accounts were approved and authorised for issue by the Board and were signed on its behalf by:

 

 

Melissa Sturgess

Chief Executive Officer

 

 

 

The notes which follow form part of these management accounts. 

Statement of Changes in Equity for the quarter ended 31 January 2024

 

 

 

Share Capital

Share Premium

Share Option Reserve

Retained Earnings

Tot

al

 

£

£

£

£

£

As at 1 November 2023

5,756,056

5,328,996

51,357

(3,752,004)

7,384,405







Loss for quarter ended 31 January 2024

-

-

-

(244,322)

(244,322)







Share Option Expense

-

-

18,859

-

18,859







Balance at 31 January 2024

5,756,056

5,328,996

70,216

(3,996,326)

7,158,942

 

The following describes the nature and purpose of each reserve within owners' equity:

 

Reserve

Description and purpose

Share capital

This represents the nominal value of shares issued.

Share premium

Amount subscribed for share capital in excess of nominal value.

Retained earnings

Cumulative net gains and losses recognised in the statement of comprehensive income.

 

 


 

The notes which follow form part of these management accounts.


Ananda Developments Plc is a public limited company limited by shares and was incorporated on 19 January 2018 with company number 13440398.  Its registered office is at 60 Gracechurch Street, London, EC3V 0HR.

 

The Company's shares are traded on the Aquis Stock Exchange Growth Market under symbol ANA and ISIN number GB00BDQPXQ60.

 

The information for period ended 31 January 2024 are unaudited.

 

Basis of preparation

 

These quarterly management accounts of Ananda have been prepared in compliance with United Kingdom Accounting Standards, including Financial Reporting Standard 102, "The Financial Reporting Standard applicable in the United Kingdom and the Republic of Ireland" ("FRS 102") and the Companies Act 2006.

 

These management accounts are prepared on a going concern basis, under the historical cost convention, as modified by the recognition of listed invests at fair value.

 

The management accounts are presented in Pounds Sterling, which is the Company's presentation and functional currency.

 

The preparation of the management accounts requires the use of certain critical accounting estimates. It also requires management to exercise its judgment in the process of applying the Company's accounting policies. The areas involving a higher degree of judgment and complexity, or areas where assumptions and estimates are significant to the management accounts are disclosed below.

 

1 Going Concern

 

The Company does not have a bank account.  Ananda's cash is held by its subsidiary companies DJT Plants Ltd and MRX Global Limited.  As at 31 January 2024, the subsidiaries jointly held cash of £84,428.

 

For this reason, it continues to adopt the going concern basis in preparing the management accounts.

 

2 Earnings per share

 

The calculation of earnings per share is based on the loss attributable to ordinary shareholders divided by the average number of shares in issue during the period.

 


 

31 January 2024

 

Earnings

 

£

Loss for the quarters ended


(244,322)

Number of shares

 

 

Weighted number of shares for the purpose of basic and diluted earnings per share


2,878,027,906

Earnings per share (pence)


(0.008p)

 

 

https://investors.anandadevelopments.com/link/YeN0kP

 

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