Nigel Wray acquires shares

Alliance Pharma PLC
10 November 2004

FOR IMMEDIATE RELEASE 10 November 2004                              

                               Alliance Pharma Plc
                                        
                                  Schedule 10 
                                        
                  Notification of Major Interests in Shares 
                                        
            Nigel Wray acquires additional shares in Alliance Pharma

                                        
1. Name of Company

Alliance Pharma Plc

 2. Name of shareholder having a major interest:

Nigel Wray

 3. Please state whether notification indicates that it is in respect of holding
    of the shareholder named in 2 above or in respect of a non-beneficial
    interest or in the case of an individual holder if it is a holding of that
    person's spouse or children under the age of 18:

Notifiable interests of:

Nigel Wray
Syncbeam Limited

 4. Name of registered holder(s) and, if more than one holder, the number of
    shares held by each of them:

Pershing Keen Nominees Limited

 5. Number of shares/amount of stock acquired:

3,500,000

 6. Percentage of issued class (excluding treasury shares):

2.38%

 7. Number of shares/amount of stock disposed :

N/A

 8. Percentage of issued class (excluding treasury shares):

N/A

 9. Class of security:

Ordinary shares of 1p each

10. Date of transaction:

28 October 2004

11. Date company informed:

28 October 2004

12. Total holding following this notification:

5,655,407

13. Total percentage holding of issued class following this notification
    (excluding treasury shares):

3.84%

14. Additional Information:

                                     -ENDS-

Company official responsible for making notification

Maddy Scott, Finance Director
01249 705 105


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