Major Interest in Shares

Alliance Pharma PLC
31 August 2007



For Immediate Release                                             31 August 2007



                              Alliance Pharma Plc
                                        
                    Notification of Major Interests in Shares


Alliance Pharma plc (AIM: APH), the speciality pharmaceutical company, was
notified  on 31 August, 2007 that the FMR Corp (Fidelity International) no
longer has an  interest in the issued share capital of the Company.

                                        -ENDS-



For further information:

Alliance Pharma plc                                        + 44 (0) 124946 6966
                                                                          
John Dawson, Chief Executive
Richard Wright, Finance Director
www.alliancepharma.co.uk

Buchanan Communications                                    + 44 (0) 20 7466 5000
Mark Court / Rebecca Skye Dietrich






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