Holding(s) in Company

Allergy Therapeutics PLC
23 March 2007


TR-1:              NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing     Allergy Therapeutics plc
shares to which voting rights are attached:

2. Reason for the notification (please tick the appropriate box or boxes)
An acquisition or disposal of voting rights
An acquisition or disposal of financial instruments which may result in the acquisition of
shares already issued to which voting rights are attached
An event changing the breakdown of voting rights                                  X
Other (please specify):

3. Full name of person(s) subject to the notification           Fidelity International Limited
obligation:

4. Full name of shareholder(s) (if different from 3.):          See 9 below

5. Date of the transaction (and date on which the threshold is  19 March 2007
crossed or reached if different):

6. Date on which issuer notified:                               21 March 2007

7. Threshold(s) that is/are crossed or reached:                 13%

8. Notified details:


A: Voting rights attached to shares
Class/type of     Situation previous to   Resulting situation after the triggering transaction
shares            the Triggering
                  transaction
 if possible      Number of   Number of   Number of  Number of voting rights  % of voting rights
using the ISIN    Shares      Voting      shares
CODE                          Rights      Direct     Direct      Indirect     Direct       Indirect
GB00B02LCQ05      10,807,373  10,807,373  0          0           10,122,973   0.00%        12.35%

ORD £0.001




B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument                           Period/ Date              that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted
N/A                  N/A             N/A                       N/A                        N/A


Total (A+B)
Number of voting rights                            % of voting rights
10,122,973                                         12.35%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:

Fidelity International Limited (FIL) is the parent holding company for various direct and indirect subsidiaries,
including Fidelity Fund Management Limited (FFML), Fidelity Investment Services Ltd (FISL), Fideilty Gestion (FIGEST),
Fideilty Investments Advisory (Korea) Limited (FIAKL), Fidelity Investments Management (Hong Kong) Limited (FIMHK),
Fidelity Pension Management (FPM), Fidelity Investments Japan (FIJ) and Fidelity Investments International (FII),
investment managers for various non-US investment companies and institutional clients.

UK Nominee                          Management Company                  Shares Held
State Str Bk and Tr Co LNDN         FPM                                 131,284
Northern Trust London               FPM                                 776,300
JP Morgan, Bournemouth              FPM                                 957,236
JP Morgan, Bournemouth              FISL                                5,649,998
JP Morgan, Bournemouth              FIL                                 1,501,512
Brown Bros Harrimn Ltd Lux          FIL                                 869,043
Bank of New York, Brussels          FPM                                 237,600

Total                                                                   10,122,973



Proxy Voting:

10. Name of the proxy holder:                                      Fidelity International Limited (FIL)

11. Number of voting rights proxy holder will cease to hold:       684,400 (Non-market transaction)

12. Date on which proxy holder will cease to hold voting rights:   19 March 2007




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