Director/PDMR Shareholding

Allergy Therapeutics PLC
16 November 2007

                            Allergy Therapeutics plc

                   ("Allergy Therapeutics" or the "Company")


                           Director/PDMR Shareholding


Allergy Therapeutics announces that on 16 November 2007 Dr Christian Gratz, a
director of the Company, exercised share options over 106,000 ordinary shares of
0.1 pence each ("Ordinary Shares") awarded pursuant to the Allergy Therapeutics
1998 Share Option Scheme and Allergy Therapeutics 2001 and Share Option Scheme
as follows:

Name of scheme:                    Allergy Therapeutics 1998 Share Option Scheme
Date of grant:                     20 October 2000
Date of exercise:                  16 November 2007
Exercise price:                    0.1 pence
Number of shares exercised:        6,000

Name of scheme:                    Allergy Therapeutics 2001 Share Option Scheme
Date of grant:                     18 December 2002
Date of exercise:                  16 November 2007
Exercise price:                    5.0 pence
Number of shares exercised:        100,000

Following the above transactions Dr Gratz now holds share options over 2,250,000
Ordinary Shares. In addition Dr Gratz holds 510,658 Ordinary Shares,
representing 0.62 per cent. of the total voting rights of the Company.

Enquiries:

Allergy Therapeutics plc                          [phone]
Ian Postlethwaite




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