Director/PDMR Shareholding

Allergy Therapeutics PLC
15 December 2005


Notification of Directors and Connected Party Interests

Allergy Therapeutics plc ("the Company")

The Company received notification on 14 December 2005 that, on 14 December 2005,
the following directors purchased ordinary shares of 0.1 pence each in the
Company at a price of 76 pence per share ("Ordinary Shares"). The director's
interests following these purchases are set out below:


Name                                 Number of Shares     Number of Shares Held   Percentage of Issued
                                         Purchased                                        Class
Keith Carter                              13,026                2,597,669                 4.13%
Ignace Goethals                           13,026                2,586,369                 4.11%
Dr Christian Graetz                        9,118                1,104,658                 1.75%
Dr Virinder Nohria                         5,211                  5,211                   0.01%
Stephen Smith                              6,513                  6,513                   0.01%



The Company also received notification that, on 14 December 2005, the following
employees of the Company purchased Ordinary Shares at a price of 76 pence per
share. The employees' interests following these purchases are set out below:


Name                                 Number of Shares     Number of Shares Held   Percentage of Issued
                                         Purchased                                        Class
Raymond Keeling                            6,513                  6,513                   0.01%
Dr Manjit Rahelu                           6,513                  6,513                   0.01%
Andrew Turnbull                           26,053                 247,872                  0.39%




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