Holding(s) in Company

Advanced Medical Solutions Grp PLC 31 May 2007 TR-1: notification of major interests in shares 1. Identity of the issuer or the underlying issuer of Advanced Medical Solutions Group Plc existing shares to which voting rights are attached 2. Reason for the notification (please tick the appropriate box or boxes) An acquisition or disposal of voting rights x An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to the AXA S.A., 25 Avenue Matignon, 75008 Paris and its notification obligation: group of companies 4. Full name of shareholder(s) (if different from 3.): 5. Date of the transaction (and date on which 29 May 2007 the threshold is crossed or reached if different): 6. Date on which issuer notified: 30 May 2007 7. Threshold(s) that is/are crossed or reached: 13% 8. Notified details: A: Voting rights attached to shares Class/type of Situation previous to Resulting situation after the triggering transaction(i) shares the Triggering transaction if possible Number of Number of Number of Number of voting rights % of voting rights using the ISIN Shares Voting shares CODE Rights Direct Indirect Direct Indirect GB0004536594 18,367,661 18,367,661 540,161 540,161 18,077,500 0.38 12.66 B: Financial Instruments Resulting situation after the triggering transactio Type of financial Expiration date Exercise/ Conversion Number of voting rights % of instrument Period/ Date that may be acquired if voting the instrument is rights exercised/ converted. - Total (A+B) Number of voting rights % of voting rights 18,617,661 13.04% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Name of Company / Fund Number of Shares % of issued share capital Sun Life Pensions Management Ltd 15,161 0.01062% Direct Sun Life Pensions Management Ltd 525,000 0.36774% Direct AXA Framlington Framlington Innovative Growth 10,000,000 7.00450% Indirect AXA Framlington Health 1,900,000 1.33085% Indirect AXA Framlington Biotech 2,550,000 1.78615% Indirect Framlington onshore private clients 2,427,500 1.70034% Indirect AWF Framlington Health 1,200,000 0.84054% Indirect Total Direct 540,161 0.37836% Total Indirect 18,077,500 12.66238% TOTAL 18,617,661 13.04074% Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: Mary Tavener 15. Contact telephone number: +44 (0)1606 545509 -------------------------- This information is provided by RNS The company news service from the London Stock Exchange
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