Holding(s) in Company

Advanced Medical Solutions Grp PLC
09 May 2008


TR-1: Notifications of Major Interests in Shares


                                                                        Advanced Medical Solutions

1. Identity of the issuer or the underlying issuer of existing
shares to which voting rights are attached:


2. Reason for notification (yes/no)
                                                                                                Yes

An acquisition or disposal of voting rights


An acquisition or disposal of financial instruments which may result in the acquisition of
shares already issued to which voting rights are attached


An event changing the breakdown of voting rights


Other (please specify):
                                                            Newton Investment Management Limited

3. Full name of person(s) subject to notification
obligation:


4. Full name of shareholder(s) (if different from
3):
                                                                         8 May 2008

5. Date of transaction (and date on which the
threshold is crossed or reached if different):
                                                                         9 May 2008

6. Date on which issuer notified:
                                                                Decrease from 5.20% to 0.13%

7. Threshold(s) that is/are crossed or reached:
8: Notified Details
A: Voting rights attached to shares


Class/type of      Situation previous to the Resulting situation after the triggering transaction
shares             triggering transaction
                   Number of    Number of    Number of   Number of voting rights  Percentage of voting
If possible use    shares       voting       shares                               rights
ISIN code                       rights

                                                         Direct     Indirect      Direct      Indirect
Ordinary 5p shares  7,441,343    7,441,343       N/A        N/A        185,000       N/A        0.13%
   GB0004536594


B: Financial Instruments


Resulting situation after the triggering transaction


Type of financial    Expiration date      Exercise/ conversion No. of voting rights  Percentage of voting
instrument                                period/date          that may be acquired  rights
                                                               (if the instrument
                                                               exercised/converted)





Total (A+B)


Number of voting rights                             Percentage of voting rights
                      185,000                                              0.13


9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively
held, if applicable:
Newton Investment Management Limited hold these shares as a discretionary investment manager


Proxy Voting:


10. Name of proxy holder:                                                    N/A


11. Number of voting rights proxy holder will cease                          N/A
to hold:
12. Date on which proxy holder will cease to hold                            N/A
voting rights:


13. Additional information:


14 Contact name:                                       Mary Tavener


15. Contact telephone name:                            [phone]






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