Holding(s) in Company

Advanced Medical Solutions Grp PLC 23 July 2007 TR-1: Notification of major interests in shares 1. Identity of the issuer or the underlying issuer of Advanced Medical Solutions Group Plc existing shares to which voting rights are attached 2. Reason for the notification (please tick the appropriate box or boxes) An acquisition or disposal of voting rights X An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): Initial notification of shareholding under Transparency Directive 3. Full name of person(s) subject to the INVESCO English & International Trust notification obligation: 4. Full name of shareholder(s) (if different from 3.): 5. Date of the transaction (and date on which 18/07/07 the threshold is crossed or reached if different): 6. Date on which issuer notified: 19/07/07 7. Threshold(s) that is/are crossed or reached: 4%, 3% 8. Notified details: A: Voting rights attached to shares Class/type of Situation previous to the Resulting situation after the triggering transaction shares Triggering transaction (i) if possible Number of Number of Number of Number of voting % of voting rights using the ISIN Shares Voting Rights shares rights CODE Direct Indirect Direct Indirect Ordinary Shares 7,000,000 7,000,000 5,500,000 5,500,000 3.84% 5p (GB0004536594) B: Financial Instruments Resulting situation after the triggering transactio Type of financial Expiration date Exercise/ Conversion Number of voting rights % of instrument Period/ Date that may be acquired if voting the instrument is rights exercised/ converted. - Total (A+B) Number of voting rights % of voting rights 5,500,000 3.84% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: JP Morgan Chase - 5,500,000 Proxy Voting: 10. Name of the proxy holder: na 11. Number of voting rights proxy holder will cease to hold: na 12. Date on which proxy holder will cease to hold voting rights: na 13. Additional information: 14. Contact name: Mary Tavener 15. Contact telephone number: +44 (0)1606 545509 -------------------------- This information is provided by RNS The company news service from the London Stock Exchange
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