Holding(s) in Company

TR-1: Notifications of Major Interests in Shares                               

1. Identity of the issuer or the underlying       Surgical Innovations Group   
issuer of existing shares to which voting rights  Plc                          
are attached:                                                                  
                                                                               
2. Reason for notification (yes/no)                                            
                                                                               
An acquisition or disposal of voting rights                           Yes      
                                                                               
An acquisition or disposal of financial instruments which may result           
in the acquisition of shares already issued to which voting rights             
are attached                                                                   
                                                                               
An event changing the breakdown of voting rights                               
                                                                               
Other (please specify):______________                                          
                                                                               
3. Full name of person(s) subject to      Deutsche Bank AG                     
notification obligation:                                                       
                                                                               
4. Full name of shareholder(s) (if                                             
different from 3):                                                             
                                                                               
5. Date of transaction (and date on which 02/11/2009                           
the threshold is crossed or reached if                                         
different):                                                                    
                                                                               
6. Date on which issuer notified:         10/11/2009                           
                                                                               
7. Threshold(s) that is/are crossed or    5%                                   
reached:                                                                       

8: Notified Details                                                             
                                                                                
A: Voting rights attached to shares                                             
                                                                                
Class/type of Situation previous to Resulting situation after the triggering    
shares        the triggering        transaction                                 
              transaction                                                       
                                                                                
If possible   Number of  Number of  Number of Number of voting   Percentage of  
use ISIN code shares     voting     shares    rights             voting rights  
                         rights                                                 
                                    Direct    Direct Indirect    Direct Indirect
                                                                                
GB40004016704 32,893,144 32,893,144 Below 3%         Below 3%           Below 3%
                                                                                

B: Financial Instruments                                                       
                                                                               
Resulting situation after the triggering transaction                           
                                                                               
Type of         Expiration     Exercise/       No. of voting    Percentage of  
financial       date           conversion      rights that may  voting rights  
instrument                     period/date     be acquired (if                 
                                               the instrument                  
                                               exercised/                      
                                               converted)                      
                                                                               

Total (A+B)                                                                    
                                                                               
Number of voting rights                 Percentage of voting rights            
                                                                               
Below 3%                                Below 3%                               

9. Chain of controlled undertakings through which the voting rights and /or the
financial instruments are effectively held, if applicable:                     
                                                                               

Proxy Voting:                                                                  
                                                                               
10. Name of proxy holder:               N/A                                    
                                                                               
11. Number of voting rights proxy       N/A                                    
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will     N/A                                    
cease to hold voting rights:                                                   

13. Additional information:             N/A                                    
                                                                               
14 Contact name:                        Natalie Brewer/Andrew Anderson         
                                                                               
15. Contact telephone name:             00 44 207 545 8533 / 8532