Disposal

Embargoed Release: 07:00hrs Friday 16 December 2005 SOPHEON PLC DEFINITIVE AGREEMENT SIGNED FOR SALE OF LESSENGER BUSINESS Sopheon plc ('Sopheon'), the international provider of software and services that improve the financial return from innovation and product development investments, announces that it has concluded a definitive agreement to sell its Lessenger business to Mavim B.V. of Noordwijk, The Netherlands. The Lessenger business provides hospital laboratory management software to approximately 70 customers based in the Netherlands, and accounted for approximately 2% of Sopheon's 2004 consolidated revenues. The divestment is consistent with Sopheon's concentration on its flagship Accolade platform. This includes continued focus on the Dutch healthcare market, where Accolade is being used to address needs in areas such as management of hospital protocols, clinical trials and innovation. As announced previously, Sopheon is actively considering how to apply these solutions to the US market. Sopheon's Chairman, Barry Mence said: 'Today's announcementfurtherunderpins our continuing focusand belief in Accolade. As the year end approaches we areconcentratingalleffortson closing new Accoladebusinessand delivering on closed orders, while concluding our planning for 2006 and beyond. Our divestment of Lessenger makes strategic sense for Sopheon, and also for Lessenger's customers. We believe they will be well served by Mavim, who are committed to the laboratory market and to continued investmentin the solution.' For further information contact: Barry Mence, Chairman Sopheon plc Tel : + 44 (0) 1483 685735 Arif Karimjee, CFO Adam Reynolds Hansard Communications Tel : + 44 (0) 207 245 1100 Andrew Tan + 44 (0) 7957 203 685 Floor Van Maaren Citigate First Financial Tel : + 31 (0) 205 754 010 About Sopheon Sopheon (LSE:SPE) is an international provider of software and services. Sopheon's Accolade® product development system automates gate- or phase-based product development (PD) processes and provides strategic decision support that allows companies to improve innovation, cut product development spending waste and shorten time to market. Sopheon's Monitor software operates as a 'reading robot' that monitors, filters, analyzes and pushes relevant content to healthcare and engineering professionals to enable effective compliance with protocols, standards and regulations. Sopheon is listed on the AIM market of the London Stock Exchange and on the Euronext in the Netherlands. For more information, please visit www.sopheon.com.

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Sopheon (SPE)
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