Total Voting Rights

Total Voting Rights 17th April, 2008 Proteome Sciences plc ("Proteome Sciences" or the "Company") In conformity with the Disclosure and Transparency Rule 5.6.1, the Company notifies the market of the following: As at the date of this announcement, the Company's issued share capital consists of 132,723,571 ordinary shares with a nominal value of 1 pence each ("Ordinary Shares"), with voting rights. The Company does not hold any Ordinary Shares in Treasury. Therefore, the total number of Ordinary Shares with voting rights is 132,723,571. The above figure of 132,723,571 Ordinary Shares may be used by shareholders in the Company as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change in their interest in, the share capital of the Company under the FSA's Disclosure and Transparency Rules. For further information please contact: Christopher Pearce or James Malthouse Proteome Sciences plc Tel: +44 (0)1932 865065 Thilo Hoffman Landsbanki Securities (UK) Limited Tel: +44 (0)207 426 9000
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