Press Release re Intronn Inc.

PROTEOME SCIENCES plc PRESS RELEASE Intronn Inc. 21 September 2007. Proteome Sciences plc ("Proteome Sciences") today announces that VIRxSYS Corporation has acquired the core technology and assets of Intronn Inc. (a company in which Proteome Sciences retains a 43 percent shareholding) in exchange for the issuance of preference stock in VIRxSYS. VIRxSYS is a private US biotechnology company founded in 1998 developing gene therapies for HIV and genetic disorders using a lentiviral vector delivery platform. VIRxSYS's initial focus was directed towards HIV and genetic diseases. Intronn brings advanced pre-clinical programmes in haemophilia and dyslipidemia that integrate extremely well and should significantly accelerate the programmes recently established by VIRxSYS in the same areas and with the ability to use SMaRTTM across a broad range of other disease applications. VIRxSYS lead application, VRX496 (a CD4 T cell treatment against HIV), successfully completed Phase I trials in November 2006 and has now moved on to Phase II trials. VRX496 continues to be the only lentiviral vector currently administered in human ethical trials approved by the US Food & Drug Administration. Both companies recognise the considerable synergy between the two technologies, with SMaRTTM providing a strong pipeline of RNA products through the VIRxSYS lentiviral vector delivery platform. By combining the two technologies in an all stock transaction, both companies will participate directly from the considerable upside potential of the combined platforms and remove duplication of costs and effort. Financial terms have not been disclosed. Proteome Sciences will keep shareholders appraised of significant developments at VIRxSYS, in particular, news relating to the Phase II clinical trials. Further details can be found in the press release at www.virxsys.com. Ends Proteome Sciences plc Christopher Pearce, Chief Executive Officer James Malthouse, Finance Director Email: christopher.pearce@proteomics.com Email: james.malthouse@proteomics.com Tel: +44 (0)1932 865065 Public Relations IKON Associates Coast Communications Adrian Shaw Matt Baldwin Tel: +44 (0)1483 535102 Tel: +44 (0)1233 503200 Mobile: +44 (0)797 9900733 Mobile: +44 (0) 7930 439739 Email: adrian@ikonassociates.com Email: matt@coastcommunications.com Nominated Adviser Landsbanki Securities (UK) Limited Thilo Hoffman - Tel: +44 (0)20 7426 9000
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