Blocklisting - Interim Review

Proteome Sciences plc                             

                          Schedule 8, Block Admission                          

                       Six Months to 25th October, 2005                        

(a) Proteome Sciences plc

(b) Approved Share Option Scheme

Unapproved Share Option Scheme (No. 2)

(c) 26th April, 2005 to 25th October, 2005

(d) 824,725 Ordinary shares of 1p each

(e) 81,829 Ordinary shares of 1p each

(f) 742,896 Ordinary shares of 1p each

(g) 1,000,000 Ordinary shares of 1p each - 25th October, 2004

(h) James Malthouse - 01932 865065