Holding(s) in Company

TR-1: Standard form for notification of major holdings

1. Issuer Details

ISIN

GB0000385517

Issuer Name

THE BIOTECH GROWTH TRUST PLC

UK or Non-UK Issuer

UK

2. Reason for Notification

An acquisition or disposal of voting rights

3. Details of person subject to the notification obligation

Name

Rathbone Investment Management Ltd

City of registered office (if applicable)

London

Country of registered office (if applicable)

United Kingdom

Name City of registered office Country of registered office
Rathbone Investment Management International St Helier Jersey

4. Details of the shareholder

Name City of registered office Country of registered office
BNP Paribas Limited London UK
Rathbone Nominees Limited London UK

5. Date on which the threshold was crossed or reached

02-Feb-2022

6. Date on which Issuer notified

03-Feb-2022

7. Total positions of person(s) subject to the notification obligation

. % of voting rights attached to shares (total of 8.A) % of voting rights through financial instruments (total of 8.B 1 + 8.B 2) Total of both in % (8.A + 8.B) Total number of voting rights held in issuer
Resulting situation on the date on which threshold was crossed or reached 5.010000 0.000000 5.010000 2061139
Position of previous notification (if applicable)

8. Notified details of the resulting situation on the date on which the threshold was crossed or reached

8A. Voting rights attached to shares

Class/Type of shares ISIN code(if possible) Number of direct voting rights (DTR5.1) Number of indirect voting rights (DTR5.2.1) % of direct voting rights (DTR5.1) % of indirect voting rights (DTR5.2.1)
GB0000385517 2061139 5.010000
Sub Total 8.A 2061139 5.010000%

8B1. Financial Instruments according to (DTR5.3.1R.(1) (a))

Type of financial instrument Expiration date Exercise/conversion period Number of voting rights that may be acquired if the instrument is exercised/converted % of voting rights
Sub Total 8.B1

8B2. Financial Instruments with similar economic effect according to (DTR5.3.1R.(1) (b))

Type of financial instrument Expiration date Exercise/conversion period Physical or cash settlement Number of voting rights % of voting rights
Sub Total 8.B2

9. Information in relation to the person subject to the notification obligation

2. Full chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held starting with the ultimate controlling natural person or legal entities (please add additional rows as necessary)

Ultimate controlling person Name of controlled undertaking % of voting rights if it equals or is higher than the notifiable threshold % of voting rights through financial instruments if it equals or is higher than the notifiable threshold Total of both if it equals or is higher than the notifiable threshold
Rathbone Investment Management 4.960000 4.960000%
Rathbone Investment Management International 0.050000 0.050000%

10. In case of proxy voting

Name of the proxy holder

The number and % of voting rights held

The date until which the voting rights will be held

11. Additional Information

none

12. Date of Completion

03-Feb-2022

13. Place Of Completion

Port of Liverpool Building, Liverpool L3 1NW”

UK 100

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