Holding(s) in Company

For filings with the FSA include the annex For filings with issuer exclude the annex TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are Avacta Group PLC attached: 2 Reason for the notification (please tick the appropriate box or boxes): An acquisition or disposal of voting rights x An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to the Rock Island Investments Ltd notification obligation: 4. Full name of shareholder(s) (if different from 3.): 5. Date of the transaction and date on which the threshold is crossed or 22 December 2010 reached: 6. Date on which issuer notified: 29 December 2010 7. Threshold(s) that is/are crossed or 4% and 3% reached: 8. Notified details: A: Voting rights attached to shares Class/type Situation previous Resulting situation after the triggering transaction of to the triggering shares transaction if possible Number Number Number Number of voting % of voting rights using of of of shares rights the ISIN Shares Voting CODE Rights Direct Direct Indirect Direct Indirect Ordinary 0.1p GB0033519546 63,014,131 63,014,131 0 0 Less than 3% B: Qualifying Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration Exercise/ Number of voting % of voting instrument date Conversion Period rights that may be rights acquired if the instrument is exercised/ converted. C: Financial Instruments with similar economic effect to Qualifying Financial Instruments Resulting situation after the triggering transaction Type of Exercise price Expiration Exercise/ Number of voting rights % of voting rights financial date Conversion instrument refers to instrument period Nominal Delta Total (A+B+C) Number of voting rights Percentage of voting rights 0 Less than 3% 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: Chris Hill 15. Contact telephone number: 07875303242
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