Holding(s) in Company

2 December 2008

Microgen plc (the "Company")

Notifiable Interests

Further to the Company's recent announcement of a decrease in its issued share
capital to 86,830,192 Ordinary Shares, the Company announces that it received
the following notifications on 1 December 2008 in compliance with the
Disclosure and Transparency Rules.



Invesco Limited

Invesco Limited is interested in 4,362,603 Ordinary Shares representing 5.02%
of the issued share capital of the Company.

The shares are registered in the name of:

                                                  No. of Ordinary Shares
                                                                            
Chase Bank                                                       371,467
                                                                            
Citibank                                                       3,991,136



Mineworker's Pension Scheme

Mineworker's Pension Scheme is interested in 4,026,692 Ordinary Shares
representing 4.64% of the issued share capital of the Company.

British Coal Staff Superannuation Scheme

British Coal Staff Superannuation Scheme is interested in 3,788,605 Ordinary
Shares representing 4.36% of the issued share capital of the Company.



If you require further information please contact:

A. Siddiqi, Company Secretary         Tel: [phone]

www.microgen.com