Director/PDMR Shareholding

2 December 2008

Microgen plc (the "Company")

Director/PDMR Shareholding

This notification is made in accordance with DR 3.1.4R (1) (a) and (b):

Microgen plc announces that, in accordance with the rules of the Microgen
Performance Share Plan 2006, awards of options over Ordinary Shares of 5p each
were made on 2 December 2008 to the following Directors of the Company:

Name of Director:                           David Sherriff                     
                                                                               
Date of Grant:                              2 December 2008                    
                                                                               
Date on which it can be exercised:          2 December 2011                    
                                                                               
Total amount paid (if any) for grant of                                     
option:                                     NIL                                   
                                                                               
Description of shares involved:             56,780 Ordinary Shares of 5p each  
                                                                               
Exercise price in pence:                    5p                                 
                                                                               
Total Number of Shares over which                                    
Options held following this notification:   1,050,000                                   



Name of Director:                           Philip Wood                        
                                                                               
Date of Grant:                              2 December 2008                    
                                                                               
Date on which it can be exercised:          2 December 2011                    
                                                                               
Total amount paid (if any) for grant of                                     
option:                                     NIL                                   
                                                                               
Description of shares involved:             50,000 Ordinary Shares of 5p each  
                                                                               
Exercise price in pence:                    5p                                 
                                                                               
Total Number of Shares over which           
Options held following this notification:   225,000                                                               
                                                                               



If you require further information please contact:

A. Siddiqi, Company Secretary Tel: [phone]

www.microgen.com