Director/PDMR Shareholding

29th February 2008

                                 Microgen plc                                  

                          Director/PDMR Shareholding                           

This notification is made in accordance with DR 3.1.4R (1)(a):

Microgen plc announces that, in accordance with the rules of the Microgen
Performance Share Plan 2006, awards of options over Ordinary Shares of 5p each
were made on 29th February 2008 to the following PDMRs:


Name of PDMR:                         Tamara Kahn                              
                                                                               
Date of Grant:                        29 February 2008                         
                                                                               
Date on which it can be exercised:    28 February 2011                         
                                                                               
Total amount paid (if any) for grant  NIL                                                                               
of option:                            
                                                                               
Description of shares involved:       50,000 Ordinary Shares of 5p each        
                                                                               
Exercise price in pence:              5p                                       
                                                                               
Total Number of Shares over which     125,000                                  
Options held following this                                                    
notification:                                                                  

Name of PDMR:                         Anjum Siddiqi                            
                                                                               
Date of Grant:                        29 February 2008                         
                                                                               
Date on which it can be exercised:    28 February 2011                         
                                                                               
Total amount paid (if any) for grant  NIL                                      
of option:                                                                     
                                                                               
Description of shares involved:       25,000 Ordinary Shares of 5p each        
                                                                               
Exercise price in pence:              5p                                       
                                                                               
Total Number of Shares over which     85,000                                   
Options held following this                                                    
notification:                                                                  


If you require further information please contact:

G.E. Liddle, Company Secretary 01252 772 313