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Xenova Group PLC (XEN)

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Wednesday 04 July, 2001

Xenova Group PLC

Holding in Company

Xenova Group PLC
4 July 2001


LETTER TO: XENOVA GROUP PLC


Companies Act 1985 (as amended):
Disclosure of Interests in Shares

In accordance with Part VI of the Companies Act 1985 (as amended) (the 'Act'),
we write to inform you that Prudential plc and certain of its subsidiary
companies have a notifiable interest in the issued share capital of your company
as detailed in the schedule below.

For purposes of S210 of the Act, the address for those companies identified in
the attached schedule is Laurence Pountney Hill London EC4R 0HH.


LETTER FROM: M&G INVESTMENT MANAGEMENT LIMITED




                 Notifiable Position for XENOVA GROUP ORD GBP0.10
                               as at 03 July 2001

Percentage holdings are calculated using an issued share capital of 139,190,000
ORD GBP0.10 shares

                  Registered Holder                  Holding      %

Prudential                                         15,337,244  11.01  Total     
                                                                      Notifiable
                                                                      Interest
                 CHASE NOMS LT A/C 14914              175,160
                 CHASE NOMS LTD                       120,000
                 CHASE NOMS LTD A/C 14922             291,935
                 CLYDESDALE BK NOMS LTD MGC         3,785,648
                 CLYDESDALE BK NOMS LTD MGIN        1,998,320
                 NORTRUST NOMS LTD                    291,935
                 PRUCLT HSBC GIS NOM(UK) PAC AC     7,151,285
                 PRUCLT HSBC GIS NOM(UK) PPL AC     1,522,961

M&G Group 
Limited                                            15,337,244  11.01

                 CHASE NOMS LT A/C 14914              175,160
                 CHASE NOMS LTD                       120,000
                 CHASE NOMS LTD A/C 14922             291,935
                 CLYDESDALE BK NOMS LTD MGC         3,785,648
                 CLYDESDALE BK NOMS LTD MGIN        1,998,320
                 NORTRUST NOMS LTD                    291,935
                 PRUCLT HSBC GIS NOM(UK) PAC AC     7,151,285
                 PRUCLT HSBC GIS NOM(UK) PPL AC     1,522,961

M&G Investment
Management
Limited                                            15,337,244  11.01

                 CHASE NOMS LT A/C 14914              175,160
                 CHASE NOMS LTD                       120,000
                 CHASE NOMS LTD A/C 14922             291,935
                 CLYDESDALE BK NOMS LTD MGC         3,785,648
                 CLYDESDALE BK NOMS LTD MGIN        1,998,320
                 NORTRUST NOMS LTD                    291,935
                 PRUCLT HSBC GIS NOM(UK) PAC AC     7,151,285
                 PRUCLT HSBC GIS NOM(UK) PPL AC     1,522,961

M&G Limited                                        15,337,244  11.01

                 CHASE NOMS LT A/C 14914              175,160
                 CHASE NOMS LTD                       120,000
                 CHASE NOMS LTD A/C 14922             291,935
                 CLYDESDALE BK NOMS LTD MGC         3,785,648
                 CLYDESDALE BK NOMS LTD MGIN        1,998,320
                 NORTRUST NOMS LTD                    291,935
                 PRUCLT HSBC GIS NOM(UK) PAC AC     7,151,285
                 PRUCLT HSBC GIS NOM(UK) PPL AC     1,522,961

The Prudential
Assurance
Company Limited                                     8,674,246   6.23

                 PRUCLT HSBC GIS NOM(UK) PAC AC     7,151,285
                 PRUCLT HSBC GIS NOM(UK) PPL AC     1,522,961