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Lipoxen PLC (XEN)

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Friday 17 March, 2006

Lipoxen PLC

Holding(s) in Company

Lipoxen PLC
17 March 2006

Lipoxen plc ('the Company')

Holding(s) in Company

The following information falls to be disclosed as required by Sections 198 to
202 of the Companies Act 1985 and Rule 17 of the AIM Rules:

Name of       Date of     Date of    Disposal          Number of     % of Issued
Beneficial    Disclosure  Disposal                     Shares held   Share
Shareholder                                                          Capital

Volantis Fd   15 March    13 March   142,764 Ordinary  2,857,378     2.93%
Prime         2006        2006       Shares at 28p     Ordinary 0.5p
Brokerage                            each              shares
Nominees Ltd
A/C 1945      

Alphagen Volantis Fd Prime Brokerage no longer had a notifiable interest in the
shares of the Company.

17 March 2006

                      This information is provided by RNS
            The company news service from the London Stock Exchange