Holding(s) in Company

Phytopharm PLC
30 June 2005

Re: Disclosure of interests in shares

In accordance with Part IV of the UK Companies Act 1985, M & G Investment
Management Limited informed us on 28th June 2005, that Prudential plc and all of
its subsidiary companies no longer has a notifiable interest in the issued share
capital of Phytopharm plc.





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