TR-1: Notifications of Major Interests in Shares
1. Identity of the issuer or the underlying issuer of existing Advanced Medical Solutions
shares to which voting rights are attached:
2. Reason for notification (yes/no)
An acquisition or disposal of voting rights Yes
An acquisition or disposal of financial instruments which may result in the acquisition of
shares already issued to which voting rights are attached
An event changing the breakdown of voting rights
Other (please specify):
3. Full name of person(s) subject to notification AXA S.A. 25 Avenue Matignon, 75008 Paris and its
obligation: group of companies
4. Full name of shareholder(s) (if different from
3):
5. Date of transaction (and date on which the 8 May 2008
threshold is crossed or reached if different):
6. Date on which issuer notified: 9 May 2008
7. Threshold(s) that is/are crossed or reached: 13%
8: Notified Details
A: Voting rights attached to shares
Class/type of Situation previous to the Resulting situation after the triggering transaction
shares triggering transaction
Number of Number of Number of Number of voting rights Percentage of voting
If possible use shares voting shares rights
ISIN code rights
Direct Indirect Direct Indirect
Ordinary 5p shares 19,182,218 19,182,218 415,161 415,161 18,167,057 0.29 12.68
GB0004536594
B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial Expiration date Exercise/ conversion No. of voting rights Percentage of voting
instrument period/date that may be acquired rights
(if the instrument
exercised/converted)
Total (A+B)
Number of voting rights Percentage of voting rights
18,582,218 12.97%
9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are
effectively held, if applicable:
Name of the Company/Fund No of shares % of issued share cap
Sun Life Pensions Mgmt Ltd 15,161 0.01
Direct
Sun Life Pensions Mgmt Ltd 400,000 0.28
Direct
AXA Framlington 10,000,000 6.99
Framlington Innovative Growth
Indirect
AXA Framlington 5,100,000 3.56
Health
Indirect
Framlington onshore private clients 2,701,500 1.89
Indirect
AWF Framlington Health 365,557 0.26
Indirect
Total Direct 415,161 0.29
Total Indirect 18,167,057 12.68
Total 18,582,218 13.36
Proxy Voting:
10. Name of proxy holder: N/A
11. Number of voting rights proxy holder will cease N/A
to hold:
12. Date on which proxy holder will cease to hold N/A
voting rights:
13. Additional information:
14 Contact name: Mary Tavener
15. Contact telephone name: +44 (0) 1606 545509