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Creon Corporation (AMED)

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Thursday 06 January, 2005

Creon Corporation

Holding(s) in Company

Creon Corporation PLC
06 January 2005

                              Creon Corporation PLC

                              Notifiable Interest


Creon Corporation PLC advises that it received notice on 5 January 2005 from
Royal Bank of Canada advising that RBC Holdings (Channel Islands) Limited, a
wholly owned subsidiary of Royal Bank of Canada has recently acquired 612,500
ordinary shares in Creon Corporation PLC representing 10% of the Company's
issued ordinary share capital.  This represents the entire holding of RBC
Holdings (Channel Islands) Limited in Creon Corporation PLC.



For further information, please contact:

Nairn Black, Noble & Company Limited               0131 225 9677




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