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AstraZeneca PLC (AZN)

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Friday 03 February, 2012

AstraZeneca PLC

Director/PDMR Shareholding

RNS Number : 7962W
AstraZeneca PLC
03 February 2012

Transaction by Person Discharging Managerial Responsibilities

Disclosure Rules DTR 3.1.4R


We hereby inform you that the interest of Simon Lowth, a Director of the Company, in the ordinary shares of AstraZeneca PLC has changed as detailed below.


On 3 February 2012, Mr Lowth sold 22,278 shares at a price of 2985 pence per share for reasons of personal financial planning.


As a result of this transaction, Mr Lowth has an interest in 239,085 shares, which represent approximately 0.02% of the Company's issued ordinary capital.



A C N Kemp

Company Secretary

3 February 2012

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